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Recombinant Human Pro-epidermal growth factor(EGF),partial (Active)

Recombinant Human Pro-epidermal growth factor(EGF),partial (Active)
产品货号:RSQ-CC004
产品规格:100ug/1mg
储存形式:冻干粉
目录价:960/3500
EGF 是目前发现的 EGFR 的主要配体之一,是一种强效生长因子,可刺激多种表皮和上皮细胞的增殖。
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EGF 是目前发现的 EGFR 的主要配体之一,是一种强效生长因子,可刺激多种表皮和上皮细胞的增殖,由于 EGF 配体与细胞外受体(例如 EGF)相结合,EGFR 二聚体化引起胞内域形成酪氨酸激酶活化,激活下游信号通路,经信号的级联反应,最终信号传递至细胞核,调控相应基因的表达,进而控制细胞生长分裂、分化、迁移与粘附等生理活动。此外,EGF还可抑制胃酸分泌,并参与创伤修复过程。EGF通过与C-erbB受体(I型酪氨酸激酶受体)相结合而传导信号,EGF 是胃肠道、甲状腺、肝脏、脑等多种类器官培养所需的细胞因子。

产品名称  Recombinant Human Pro-epidermal growth factor(EGF),partial (Active)
货号 RSQ-CC004

蛋白构建

Uniorot ID:P01133(971-1023aa)
别名 Pro-Epidermal Growth Factor; EGF; Epidermal Growth Factor; Urogastrone
表达宿主 E.coli
种属 Homo sapiens (Human)
纯度 Greater than 95% as determined by SDS-PAGE.
内毒素 Less than 1.0 EU/µg as determined by LAL method.
缓冲液 Lyophilized from a 0.2 μm Filtered 20 mM Tris-HCl, 200 mM NaCl, pH 8.0
存储 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
类别 Protein
用途 For research use only